Methoxybenzoic acids and derivatives
Aobchem Methyl 4-isopropoxy-2-methoxybenzoate | 95% | CAS 365526-27-8 | C12H16O4 | 500mg
Methyl 4-isopropoxy-2-methoxybenzoate | 95% | CAS 365526-27-8 | C12H16O4 | 500mg
Aobchem 2 3 6-Trifluoro-4-methoxybenzoic acid | 97% | CAS 1804097-22-0 | C8H5F3O3 | 1g
2 3 6-Trifluoro-4-methoxybenzoic acid | 97% | CAS 1804097-22-0 | C8H5F3O3 | 1g
Aobchem 4-Methoxy-N 3-dimethylbenzenesulfonamide | 95% | CAS 677722-10-0 | C9H13NO3S | 5g
4-Methoxy-N 3-dimethylbenzenesulfonamide | 95% | CAS 677722-10-0 | C9H13NO3S | 5g
Aobchem 2-Methoxy-1-(3-propylphenyl)ethanone | 95% | CAS 1598493-48-1 | C12H16O2 | 500mg
2-Methoxy-1-(3-propylphenyl)ethanone | 95% | CAS 1598493-48-1 | C12H16O2 | 500mg
Aobchem 4-Methoxy-3-methylbenzenesulfonic acid hydrazide | 95% | CAS 1156892-78-2 | C8H12N2O3S | 250mg
4-Methoxy-3-methylbenzenesulfonic acid hydrazide | 95% | CAS 1156892-78-2 | C8H12N2O3S | 250mg
Medchemexpress LLC Ro 08-2750 | 37854-59-4 | 98.01% | 270.24 | 10 MG
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor that binds to NGF with an IC50 of approximately 1 μM. It selectively inhibits NGF binding to p75NTR over TRKA. Ro 08-2750 is also a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM.
- Binds to the NGF dimer, potentially inducing a conformational change that prevents NGF from binding to p75NTR.
- Completely rescues cells from NGF-induced SK-N-MC 103 cell death at 10 nM.
- Increases differentiation and apoptosis in myeloid leukemia cells at 5-10 μM (8 hours).
- Inhibits survival of human AML lines and patient cells.
- Inhibits MSI2 RNA-binding and alters MSI2 gene signature.
- Inhibits leukemogenesis in a myeloid leukemia model in vivo at 13.75 mg/kg (i.p.).
- Reduces c-MYC levels and disease burden in a myeloid leukemia model.
Aobchem 2 6-Dichloro-4-methoxybenzoic acid | ≥97% | CAS 94278-69-0 | C8H6Cl2O3 | 250mg
2 6-Dichloro-4-methoxybenzoic acid | ≥97% | CAS 94278-69-0 | C8H6Cl2O3 | 250mg
Aobchem Methyl 4-iodo-2-methylbenzoate | ≥95% | CAS 103440-53-5 | C9H9IO2 | 5g
Methyl 4-iodo-2-methylbenzoate | ≥95% | CAS 103440-53-5 | C9H9IO2 | 5g
Aobchem 1-Bromo-2-(difluoromethoxy)-3-methylbenzene | ≥95% | CAS 954236-08-9 | C8H7BrF2O | 500mg
1-Bromo-2-(difluoromethoxy)-3-methylbenzene | ≥95% | CAS 954236-08-9 | C8H7BrF2O | 500mg
Aobchem -Cyclopropyl-3 4-dimethoxybenzenemethanol | 95% | CAS 1181579-96-3 | C12H16O3 | 250mg
-Cyclopropyl-3 4-dimethoxybenzenemethanol | 95% | CAS 1181579-96-3 | C12H16O3 | 250mg
Aobchem 2-Methoxy- 3-dimethylbenzenemethanol | 95% | CAS 1226364-07-3 | C10H14O2 | 5g
2-Methoxy- 3-dimethylbenzenemethanol | 95% | CAS 1226364-07-3 | C10H14O2 | 5g
Aobchem (3 5-Difluoro-4-(methylsulfonyl)phenyl)boronic acid | 95% | CAS 2765195-62-6 | C7H7BF2O4S | 1g
(3 5-Difluoro-4-(methylsulfonyl)phenyl)boronic acid | 95% | CAS 2765195-62-6 | C7H7BF2O4S | 1g
Aobchem (3 5-Difluoro-4-(methylsulfonyl)phenyl)boronic acid | 95% | CAS 2765195-62-6 | C7H7BF2O4S | 250mg
(3 5-Difluoro-4-(methylsulfonyl)phenyl)boronic acid | 95% | CAS 2765195-62-6 | C7H7BF2O4S | 250mg
Aobchem (2-Methoxy-1 3-phenylene)diboronic acid | 95% | CAS 1100746-83-5 | C7H10B2O5 | 1g
(2-Methoxy-1 3-phenylene)diboronic acid | 95% | CAS 1100746-83-5 | C7H10B2O5 | 1g
Aobchem 4-(Difluoromethoxy)-3-fluoro-5-methoxybenzoic acid | 95% | CAS 2167670-40-6 | C9H7F3O4 | 500mg
4-(Difluoromethoxy)-3-fluoro-5-methoxybenzoic acid | 95% | CAS 2167670-40-6 | C9H7F3O4 | 500mg